About the Authors

Liis Uusküla

Affiliation Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Jaana Männik

Affiliations Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Department of Biochemistry, Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee, United States of America

Kristiina Rull

Affiliations Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, Department of Obstetrics and Gynecology, Tartu University Hospital, Tartu, Estonia

Ave Minajeva

Affiliation Department of Pathology, Tartu University Hospital, Tartu, Estonia

Sulev Kõks

Affiliation Department of Physiology, Center of Translational Medicine, University of Tartu, Tartu, Estonia

Pille Vaas

Affiliation Department of Obstetrics and Gynecology, Tartu University Hospital, Tartu, Estonia

Pille Teesalu

Affiliation Department of Obstetrics and Gynecology, Tartu University Hospital, Tartu, Estonia

Jüri Reimand

maris.laan@ut.ee (ML); Juri.Reimand@utoronto.ca (JR)

Affiliation Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

Maris Laan

maris.laan@ut.ee (ML); Juri.Reimand@utoronto.ca (JR)

Affiliation Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ML LU JR KR JM. Performed the experiments: LU KR JM AM. Analyzed the data: JR SK LU JM. Contributed reagents/materials/analysis tools: ML JR. Wrote the paper: LU ML JR JM. Large-scle bioinformatic data analysis: JR. Recruitment of the study participants and collection of clinical information: PV PT KR. Collection and management of the biological samples of the study: PV PT KR ML JM. Interpretation of the study data: ML LU JM JR KR AM. Critical reading and commenting of the manuscript: KR AM SK PV. Approval of the final manuscript: LU JM KR AM SK PV PT JR ML.