Low Dose Nicotine and Antagonism of β2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice

Shawn M. Anderson; Darlene H. Brunzell

doi:10.1371/journal.pone.0048665

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Open Access

Peer-reviewed

Research Article

Low Dose Nicotine and Antagonism of β2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice

Shawn M. Anderson,

Affiliation Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
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Darlene H. Brunzell

* E-mail: dbrunzell@vcu.edu

Affiliations Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America, Interdepartmental Neuroscience Graduate Program, and Institute for Drug and Alcohol Studies, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯

Low Dose Nicotine and Antagonism of β2 Subunit Containing Nicotinic Acetylcholine Receptors Have Similar Effects on Affective Behavior in Mice

Shawn M. Anderson,
Darlene H. Brunzell

Published: November 7, 2012
https://doi.org/10.1371/journal.pone.0048665

About the Authors

Shawn M. Anderson

Affiliation Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America

Darlene H. Brunzell

* E-mail: dbrunzell@vcu.edu

Affiliations Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America, Interdepartmental Neuroscience Graduate Program, and Institute for Drug and Alcohol Studies, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DHB SMA. Performed the experiments: SMA. Analyzed the data: DHB SMA. Wrote the paper: DHB SMA. Interpreted the data: DHB SMA.

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Nicotine
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Animal behavior
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Mice
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Nicotinic acetylcholine receptors
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Biological locomotion
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Conditioned response
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Behavior
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Nicotine replacement therapy
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