Depletion of the C. elegans NAC Engages the Unfolded Protein Response, Resulting in Increased Chaperone Expression and Apoptosis

Paul T. Arsenovic; Anthony T. Maldonado; Vaughn D. Colleluori; Tim A. Bloss

doi:10.1371/journal.pone.0044038

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Peer-reviewed

Research Article

Depletion of the C. elegans NAC Engages the Unfolded Protein Response, Resulting in Increased Chaperone Expression and Apoptosis

Paul T. Arsenovic,
Anthony T. Maldonado,
Vaughn D. Colleluori,
Tim A. Bloss

* E-mail: blossta@jmu.edu

Affiliation Department of Biology, James Madison University, Harrisonburg, Virginia, United States of America
⨯

Depletion of the C. elegans NAC Engages the Unfolded Protein Response, Resulting in Increased Chaperone Expression and Apoptosis

Paul T. Arsenovic,
Anthony T. Maldonado,
Vaughn D. Colleluori,
Tim A. Bloss

Published: September 5, 2012
https://doi.org/10.1371/journal.pone.0044038

About the Authors

Paul T. Arsenovic

Anthony T. Maldonado

Vaughn D. Colleluori

Tim A. Bloss

* E-mail: blossta@jmu.edu

Affiliation Department of Biology, James Madison University, Harrisonburg, Virginia, United States of America

Competing Interests

Tim A. Bloss is an author on patent# 20060199781 “Assays based on BTF3 activity”.

Author Contributions

Conceived and designed the experiments: PTA TAB. Performed the experiments: PTA TAB ATM VDC. Analyzed the data: PTA TAB ATM VDC. Contributed reagents/materials/analysis tools: PTA TAB ATM VDC. Wrote the paper: PTA TAB.

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Caenorhabditis elegans
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Cellular stress responses
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Embryos
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Thermal stresses
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Apoptosis
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Lysosomes
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Heat shock response
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Transcription factors
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