About the Authors
- Gustavo Arruda Bezerra
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Contributed equally to this work with: Gustavo Arruda Bezerra, Elena Dobrovetsky
Affiliation Institute of Molecular Biosciences, University of Graz, Graz, Austria
- Elena Dobrovetsky
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Contributed equally to this work with: Gustavo Arruda Bezerra, Elena Dobrovetsky
Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Aiping Dong
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Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Almagul Seitova
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Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Lissete Crombett
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Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Lisa M. Shewchuk
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Affiliation GlaxoSmithKline, Computational and Structural Chemistry, North Carolina, United States of America
- Annie M. Hassell
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Affiliation GlaxoSmithKline, Computational and Structural Chemistry, North Carolina, United States of America
- Sharon M. Sweitzer
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Affiliation GlaxoSmithKline, Biological Reagents and Assay Development, Collegeville, Pennsylvania, United States of America
- Thomas D. Sweitzer
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Affiliation GlaxoSmithKline, Biological Reagents and Assay Development, Collegeville, Pennsylvania, United States of America
- Patrick J. McDevitt
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Affiliation GlaxoSmithKline, Biological Reagents and Assay Development, Collegeville, Pennsylvania, United States of America
- Kyung O. Johanson
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Affiliation GlaxoSmithKline, Biological Reagents and Assay Development, Collegeville, Pennsylvania, United States of America
- Karen M. Kennedy-Wilson
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Affiliation GlaxoSmithKline, Biological Reagents and Assay Development, Collegeville, Pennsylvania, United States of America
- Doug Cossar
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Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Alexey Bochkarev
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Affiliation Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
- Karl Gruber
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* E-mail: karl.gruber@uni-graz.at (KG); sirano.dhepaganon@utoronto.ca (SD-P)
Affiliation Institute of Molecular Biosciences, University of Graz, Graz, Austria
- Sirano Dhe-Paganon
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* E-mail: karl.gruber@uni-graz.at (KG); sirano.dhepaganon@utoronto.ca (SD-P)
Affiliations Structural Genomics Consortium, University of Toronto, MaRS Centre, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, MaRS Centre, Toronto, Ontario, Canada
Competing Interests
The work was funded in part by the companies GlaxoSmithKline and Merck & Co, Inc. In addition, co-authors LMS, AMH, SMS, TDS, PJM, KOJ, and KMK-W are employees of the commercial funder GlaxoSmithKline. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: GAB ED LMS SMS KOJ SD-P. Performed the experiments: GAB ED AD AS LC LMS AMH PJM KMK-W TDS. Analyzed the data: GAB ED AD LMS SMS KOJ DC AB KG SD-P. Wrote the paper: GAB AB KG SD-P.