About the Authors

James A. Gregory

Affiliation Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America

Fengwu Li

Affiliation Division of Infectious Disease, Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Lauren M. Tomosada

Affiliation Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America

Chesa J. Cox

Affiliation Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America

Aaron B. Topol

Affiliation Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America

Joseph M. Vinetz

Affiliation Division of Infectious Disease, Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Stephen Mayfield

smayfield@ucsd.edu

Affiliation Division of Biological Sciences, and the San Diego Center for Algae Biotechnology, University of California San Diego, California, United States of America

Competing Interests

Stephen Mayfield has a financial interest in Sapphire Energy. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JAG JMV SM. Performed the experiments: JAG LT CC FL AT. Analyzed the data: JAG. Contributed reagents/materials/analysis tools: JAG FL. Wrote the paper: JAG. Constructed and validated algae strains, performed mouse work, CD spectroscopy, immunofluorescence, and microscopy: JAG. Grew and harvested algae: JAG CC. Purified recombinant protein: JAG LT. Performed immunoblots and silver staining: JAG LT CC. Performed ELISAs: JAG AT. Cultured P. falciparum parasites and performed SMFA: FL.