About the Authors

Gesine Paul

Contributed equally to this work with: Gesine Paul, Ilknur Özen

gesine.paul@med.lu.se

Affiliations Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden, Department of Neurology, Scania University Hospital, Lund, Sweden, Translational Neurology Group, Department of Clinical Sciences, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Ilknur Özen

Contributed equally to this work with: Gesine Paul, Ilknur Özen

Affiliations Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden, Translational Neurology Group, Department of Clinical Sciences, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Nicolaj S. Christophersen

Affiliation Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Thomas Reinbothe

Affiliation Lund University Diabetes Centre, Scania University Hospital, Malmö, Sweden

Johan Bengzon

Affiliation Department of Neurosurgery, Scania University Hospital and Lund Stem Cell Center, Lund University, Lund, Sweden

Edward Visse

Affiliation The Rausing Laboratory, Department of Clinical Medicine, Lund University, Lund, Sweden

Katarina Jansson

Affiliation NeuroNova AB, Stockholm, Sweden

Karin Dannaeus

Affiliation NeuroNova AB, Stockholm, Sweden

Catarina Henriques-Oliveira

Affiliation Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Laurent Roybon

Affiliation Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Sergey V. Anisimov

Affiliation Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden

Erik Renström

Affiliation Lund University Diabetes Centre, Scania University Hospital, Malmö, Sweden

Mikael Svensson

Affiliation Department of Neurosurgery, Karolinska Hospital, Stockholm, Sweden

Anders Haegerstrand

Affiliation NeuroNova AB, Stockholm, Sweden

Patrik Brundin

Affiliations Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden, Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

Competing Interests

The following co-authors are full-time employees of NeuroNova AB: K.D., K.J. and A.H. NeuroNova AB is a small Swedish biopharmaceutical company pursuing clinical trials in Parkinson's disease and Amyotrophic Lateral Sclerosis (www.neuronova.com). The company has a general interest in understanding the regenerative capacity of the adult brain but is not pursuing strategies related to commercialization of cultured stem cells or therapies based on stem cell/progenitor transplantation. The company has not sponsored the work performed at the academic institutions. The company employees being co-authors on the manuscript have not been influenced by commercial interest interpreting the data. The authors being employees at NeuroNova AB does also not alter the authors' adherence to all PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GP IÖ AH PB KJ KD. Performed the experiments: GP IÖ TR SA NSC LR CHO KJ KD. Analyzed the data: GP IÖ TR NSC EV AH PB ER. Contributed reagents/materials/analysis tools: JB MS. Wrote the paper: GP IÖ EV PB JB.