About the Authors
- Stephanie J. Soscia
-
Affiliations Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
- James E. Kirby
-
Affiliation Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
- Kevin J. Washicosky
-
Affiliation Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
- Stephanie M. Tucker
-
Affiliation Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
- Martin Ingelsson
-
Affiliation Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden
- Bradley Hyman
-
Affiliations Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
- Mark A. Burton
-
Affiliations Molecular Aging and Developmental Laboratory, Photonics Center, College of Engineering, Boston University School of Medicine, Boston University, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University, Boston, Massachusetts, United States of America
- Lee E. Goldstein
-
Affiliations Molecular Aging and Developmental Laboratory, Photonics Center, College of Engineering, Boston University School of Medicine, Boston University, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University, Boston, Massachusetts, United States of America
- Scott Duong
-
Affiliation Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
- Rudolph E. Tanzi
-
* E-mail: tanzi@helix.mgh.harvard.edu
Affiliations Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
- Robert D. Moir
-
Affiliations Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease and Department of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
Dr Tanzi is a consultant to and holds stock options in Prana Biotechnology.
Author Contributions
Conceived and designed the experiments: SJS JEK RET RDM. Performed the experiments: SJS KJW SMT MAB. Analyzed the data: SJS JEK KJW LEG SD RET RDM. Contributed reagents/materials/analysis tools: MI BTH LEG. Wrote the paper: SJS JEK RET RDM.