About the Authors

Yi-Chun Loraine Tung

Affiliation University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, United Kingdom

Eduard Ayuso

Contributed equally to this work with: Eduard Ayuso, Xiaoye Shan

Affiliations Center of Animal Biotechnology and Gene Therapy and Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain

Xiaoye Shan

Contributed equally to this work with: Eduard Ayuso, Xiaoye Shan

Affiliation University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, United Kingdom

Fatima Bosch

Affiliations Center of Animal Biotechnology and Gene Therapy and Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain

Stephen O'Rahilly

so104@medschl.cam.ac.uk (SO); gshy2@cam.ac.uk (GSHY)

Affiliation University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, United Kingdom

Anthony P. Coll

Affiliation University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, United Kingdom

Giles S. H. Yeo

so104@medschl.cam.ac.uk (SO); gshy2@cam.ac.uk (GSHY)

Affiliation University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YCLT EA FB SO APC GSHY. Performed the experiments: YCLT XS. Analyzed the data: YCLT. Contributed reagents/materials/analysis tools: YCLT EA FB. Wrote the paper: YCLT SO APC GSHY.