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Open Access
Peer-reviewed
Research Article
Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus
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Christopher G. Bell ,
Contributed equally to this work with: Christopher G. Bell, Sarah Finer, Cecilia M. Lindgren
* E-mail: christopher.bell@ucl.ac.uk
Affiliation Medical Genomics, UCL Cancer Institute, University College London, London, United Kingdom
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Sarah Finer ,
Contributed equally to this work with: Christopher G. Bell, Sarah Finer, Cecilia M. Lindgren
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Cecilia M. Lindgren ,
Contributed equally to this work with: Christopher G. Bell, Sarah Finer, Cecilia M. Lindgren
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Gareth A. Wilson,
Affiliation Medical Genomics, UCL Cancer Institute, University College London, London, United Kingdom
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Vardhman K. Rakyan,
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Andrew E. Teschendorff,
Affiliation Medical Genomics, UCL Cancer Institute, University College London, London, United Kingdom
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Pelin Akan,
Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom
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Elia Stupka,
Affiliations Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, Comparative Genomics, UCL Cancer Institute, University College London, London, United Kingdom
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Thomas A. Down,
Affiliations Gurdon Institute, University of Cambridge, Cambridge, United Kingdom, Department of Genetics, University of Cambridge, Cambridge, United Kingdom
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Inga Prokopenko,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Ian M. Morison,
Affiliation Pathology Department, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
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Jonathan Mill,
Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
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Ruth Pidsley,
Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
⨯ - International Type 2 Diabetes 1q Consortium,
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Panos Deloukas,
Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom
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Timothy M. Frayling,
Affiliation Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, United Kingdom
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Andrew T. Hattersley,
Affiliation Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, United Kingdom
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Mark I. McCarthy ,
¶These authors also contributed equally to this work.
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Stephan Beck ,
¶These authors also contributed equally to this work.
Affiliation Medical Genomics, UCL Cancer Institute, University College London, London, United Kingdom
⨯ - [ ... ],
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Graham A. Hitman
¶These authors also contributed equally to this work.
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus
- Christopher G. Bell,
- Sarah Finer,
- Cecilia M. Lindgren,
- Gareth A. Wilson,
- Vardhman K. Rakyan,
- Andrew E. Teschendorff,
- Pelin Akan,
- Elia Stupka,
- Thomas A. Down,
- Inga Prokopenko
- Published: November 18, 2010
- https://doi.org/10.1371/journal.pone.0014040