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The Use of Directed Evolution to Create a Stable and Immunogenic Recombinant BCG Expressing a Modified HIV-1 Gag Antigen

  • Rosamund Chapman ,

    Contributed equally to this work with: Rosamund Chapman, William R. Bourn

    Ros.Chapman@uct.ac.za

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • William R. Bourn ,

    Contributed equally to this work with: Rosamund Chapman, William R. Bourn

    Current address: Kapabiosystems, Cape Town, South Africa

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Enid Shephard,

    Affiliations Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, Medical Research Council, Cape Town, South Africa, Department of Medicine Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Helen Stutz,

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Nicola Douglass,

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Thandi Mgwebi,

    Current address: Human Capacity Programme, National Research Foundation, Pretoria, South Africa

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Ann Meyers,

    Affiliation Department of Molecular and Cell Biology, Faculty Of Science, University of Cape Town, Cape Town, South Africa

  • Nyasha Chin'ombe,

    Current address: Department of Medical Microbiology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe

    Affiliation Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

  • Anna-Lise Williamson

    Affiliations Division of Virology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, National Health Laboratory Services, Cape Town, South Africa

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