Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy

• Shannon E. Boye ,

  * E-mail: jacobsos@mail.med.upenn.edu (SGJ); shaire@ufl.edu (SEB)

  Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Wei-Chieh Huang,

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Alejandro J. Roman,

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Alexander Sumaroka,

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Sanford L. Boye,

  Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Renee C. Ryals,

  Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Melani B. Olivares,

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Qing Ruan,

  Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Budd A. Tucker,

  Affiliation Stephen A. Wynn Institute for Vision Research, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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• Edwin M. Stone,

  Affiliations Stephen A. Wynn Institute for Vision Research, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America, Howard Hughes Medical Institute, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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• Anand Swaroop,

  Affiliation Neurobiology-Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Artur V. Cideciyan,

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• William W. Hauswirth,

  Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Samuel G. Jacobson

  * E-mail: jacobsos@mail.med.upenn.edu (SGJ); shaire@ufl.edu (SEB)

  Affiliation Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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