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Open Access

Peer-reviewed

Research Article

Molecular Topology as Novel Strategy for Discovery of Drugs with Aβ Lowering and Anti-Aggregation Dual Activities for Alzheimer’s Disease

  • Jun Wang,

    Affiliations Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America, Geriatric Research, Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York New York, United States of America

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  • David Land,

    Affiliation Medisyn Technologies, Inc. Minnetonka, Minnesota, United States of America

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  • Kenjiro Ono,

    Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University, Kanazawa, Japan

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  • Jorge Galvez,

    Affiliation Molecular Topology & Drug Design Unit, University of Valencia, Valencia, Spain

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  • Wei Zhao,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Prashant Vempati,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • John W. Steele,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Alice Cheng,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Masahito Yamada,

    Affiliation Department of Neurology and Neurobiology of Aging, Kanazawa University, Kanazawa, Japan

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  • Samara Levine,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Paolo Mazzola,

    Affiliation Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Giulio M. Pasinetti

    giulio.pasinetti@mssm.edu

    Affiliations Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America, Geriatric Research, Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York New York, United States of America

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