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Open Access

Peer-reviewed

Research Article

Attenuation of Hedgehog Acyltransferase-Catalyzed Sonic Hedgehog Palmitoylation Causes Reduced Signaling, Proliferation and Invasiveness of Human Carcinoma Cells

  • Antonios D. Konitsiotis ,

    Contributed equally to this work with: Antonios D. Konitsiotis, Shu-Chun Chang

    Affiliation Molecular Medicine Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Shu-Chun Chang ,

    Contributed equally to this work with: Antonios D. Konitsiotis, Shu-Chun Chang

    Current address: Department of Biological Sciences, National University of Singapore, Singapore, Singapore

    Affiliation Molecular Medicine Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom

    ⨯
  • Biljana Jovanović,

    Current address: Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

    Affiliation Molecular Medicine Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Paulina Ciepla,

    Affiliations Department of Chemistry, Imperial College London, London, United Kingdom, Institute of Chemical Biology, Imperial College London, London, United Kingdom

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  • Naoko Masumoto,

    Affiliations Department of Chemistry, Imperial College London, London, United Kingdom, Institute of Chemical Biology, Imperial College London, London, United Kingdom

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  • Christopher P. Palmer,

    Affiliation Institute for Health Research and Policy, London Metropolitan University, London, United Kingdom

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  • Edward W. Tate,

    Affiliations Department of Chemistry, Imperial College London, London, United Kingdom, Institute of Chemical Biology, Imperial College London, London, United Kingdom

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  • John R. Couchman,

    Affiliation Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark

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  • Anthony I. Magee

    t.magee@imperial.ac.uk

    Affiliations Molecular Medicine Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, Institute of Chemical Biology, Imperial College London, London, United Kingdom

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