Ubiquilin-1 Overexpression Increases the Lifespan and Delays Accumulation of Huntingtin Aggregates in the R6/2 Mouse Model of Huntington's Disease

• Nathaniel Safren ,

  Contributed equally to this work with: Nathaniel Safren, Amina El Ayadi

  Affiliations Neuroscience Graduate Program, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Center for Biomedical Engineering and Technology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

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• Amina El Ayadi ,

  Contributed equally to this work with: Nathaniel Safren, Amina El Ayadi

  Affiliation Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Lydia Chang,

  Affiliations Center for Biomedical Engineering and Technology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

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• Chantelle E. Terrillion,

  Affiliations Neuroscience Graduate Program, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Psychiatry, School of Medicine University of Maryland, Baltimore, Maryland, United States of America

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• Todd D. Gould,

  Affiliations Neuroscience Graduate Program, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Psychiatry, School of Medicine University of Maryland, Baltimore, Maryland, United States of America, Department of Pharmacology, School of Medicine University of Maryland, Baltimore, Maryland, United States of America

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• Darren F. Boehning,

  Affiliation Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Mervyn J. Monteiro

  * E-mail: monteiro@umaryland.edu

  Affiliations Neuroscience Graduate Program, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Center for Biomedical Engineering and Technology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America, Department of Anatomy and Neurobiology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

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