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Inhibiting AKT Phosphorylation Employing Non-Cytotoxic Anthraquinones Ameliorates TH2 Mediated Allergic Airways Disease and Rhinovirus Exacerbation

  • Caio Cesar de Souza Alves,

    Affiliations Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Minas Gerais, Brazil, Experimental&Translational Respiratory Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Adam Collison,

    Affiliations Experimental&Translational Respiratory Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Luke Hatchwell,

    Affiliations Experimental&Translational Respiratory Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Maximilian Plank,

    Affiliation Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Matthew Morten,

    Affiliations Experimental&Translational Respiratory Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Paul S. Foster,

    Affiliation Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia

  • Sebastian L. Johnston,

    Affiliation Airway Disease Infection Section, National Heart and Lung Institute, Medical Research Council & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom

  • Cristiane França da Costa,

    Affiliation Department of Chemistry, Federal University of Juiz de Fora, Minas Gerais, Brazil

  • Mauro Vieira de Almeida,

    Affiliation Department of Chemistry, Federal University of Juiz de Fora, Minas Gerais, Brazil

  • Henrique Couto Teixeira,

    Affiliation Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Minas Gerais, Brazil

  • Ana Paula Ferreira ,

    Joerg.mattes@newcastle.edu.au (JM); ana.paula@ufjf.edu.br (APF)

    Affiliation Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Minas Gerais, Brazil

  • Joerg Mattes

    Joerg.mattes@newcastle.edu.au (JM); ana.paula@ufjf.edu.br (APF)

    Affiliations Experimental&Translational Respiratory Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Priority Research Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia, Paediatric Respiratory & Sleep Medicine Unit, Newcastle Children’s Hospital, Newcastle, Australia

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