A Quantitative Assessment of Costimulation and Phosphatase Activity on Microclusters in Early T Cell Signaling

• J. Joris Witsenburg,

  Affiliation Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Heike Glauner,

  Affiliation Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Jörg P. Müller,

  Affiliation Institute for Molecular Cell Biology, Jena University Hospital, Jena, Germany

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• Johannes M. M. Groenewoud,

  Affiliation Department of Medical Technology Assessment, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Günter Roth,

  Affiliations Laboratory for MEMS Applications, Department of Microsystems Engineering (IMTEK), Albert Ludwigs University, Freiburg, Germany, BIOSS Centre for Biological Signalling Studies, Albert Ludwigs University, Freiburg, Germany

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• Frank-Dietmar Böhmer,

  Affiliation Institute for Molecular Cell Biology, Jena University Hospital, Jena, Germany

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• Merel J. W. Adjobo-Hermans,

  Affiliation Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Roland Brock

  * E-mail: R.Brock@ncmls.ru.nl

  Affiliation Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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