Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations

• Zhijun Zhang,

  Current address: Neuroscience and Neuroengineering Research Center, Med-X Research Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

  Affiliation Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Sandra Almeida,

  Affiliation Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Yubing Lu,

  Affiliation Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Agnes L. Nishimura,

  Affiliation Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom

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• Lingtao Peng,

  Affiliations Department of Biological Chemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Howard Hughes Medical Institute, Worcester, Massachusetts, United States of America

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• Danqiong Sun,

  Current address: System Biosciences, Mountain View, California, United States of America

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Bei Wu,

  Affiliation Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts, United States of America

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• Anna M. Karydas,

  Affiliation Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

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• Maria C. Tartaglia,

  Current address: Krembil Neuroscience Centre and Department of Neurology, University of Toronto, Canada

  Affiliation Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

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• Jamie C. Fong,

  Affiliation Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

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• Bruce L. Miller,

  Affiliation Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

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• Robert V. Farese Jr,

  Affiliations Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America, Departments of Medicine and Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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• Melissa J. Moore,

  Affiliations Department of Biological Chemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Howard Hughes Medical Institute, Worcester, Massachusetts, United States of America

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• Christopher E. Shaw,

  Affiliation Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom

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• Fen-Biao Gao

  * E-mail: fen-biao.gao@umassmed.edu

  Affiliation Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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