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Open Access

Peer-reviewed

Research Article

Unique Association between Global DNA Hypomethylation and Chromosomal Alterations in Human Hepatocellular Carcinoma

  • Naoshi Nishida ,

    naoshi@med.kindai.ac.jp

    Affiliations Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan, Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan

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  • Masatoshi Kudo,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Takafumi Nishimura,

    Affiliation Outpatient Oncology Unit, Kyoto University Hospital, Kyoto, Japan

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  • Tadaaki Arizumi,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Masahiro Takita,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Satoshi Kitai,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Norihisa Yada,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Satoru Hagiwara,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Tatsuo Inoue,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Yasunori Minami,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Kazuomi Ueshima,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Toshiharu Sakurai,

    Affiliation Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan

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  • Naosuke Yokomichi,

    Affiliation Department of Gastroenterological Surgery and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

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  • Takeshi Nagasaka,

    Affiliation Department of Gastroenterological Surgery and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan

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  • Ajay Goel

    Affiliation Division of Gastroenterology, Department of Internal Medicine and Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Centre, Dallas, Texas, United States of America

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