An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population

• Alison P. Klein ,

  * E-mail: aklein1@jhmi.edu

  Affiliations Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America, Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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• Sara Lindström,

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Julie B. Mendelsohn,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Emily Steplowski,

  Affiliation Information Management Services, Silver Spring, Maryland, United States of America

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• Alan A. Arslan,

  Affiliations Department of Obstetrics and Gynecology, New York University School of Medicine, New York, New York, United States of America, Department of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America, New York University Cancer Institute, New York, New York, United States of America

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• H. Bas Bueno-de-Mesquita,

  Affiliations National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, The Netherlands

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• Charles S. Fuchs,

  Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Steven Gallinger,

  Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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• Myron Gross,

  Affiliation Department of Laboratory Medicine/Pathology, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Kathy Helzlsouer,

  Affiliations Prevention and Research Center, Mercy Medical Center, Baltimore, Maryland, United States of America, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States of America

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• Elizabeth A. Holly,

  Affiliation Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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• Eric J. Jacobs,

  Affiliation Department of Epidemiology, American Cancer Society, Atlanta, Georgia, United States of America

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• Andrea LaCroix,

  Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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• Donghui Li,

  Affiliation Department of Gastrointestinal Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America

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• Margaret T. Mandelson,

  Affiliations Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Group Health Center for Health Studies, Seattle, Washington, United States of America

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• Sara H. Olson,

  Affiliation Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Gloria M. Petersen,

  Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

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• Harvey A. Risch,

  Affiliation Department of Epidemiology and Public Health, Yale University School of Public Health, School of Medicine, New Haven, Connecticut, United States of America

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• Rachael Z. Stolzenberg-Solomon,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Wei Zheng,

  Affiliation Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, United States of America

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• Laufey Amundadottir,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Demetrius Albanes,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Naomi E. Allen,

  Affiliations Cancer Epidemiology Unit, University of Oxford, Nuffield department of Clinical Medicine, Oxford, United Kingdom, UK Biobank, Oxford, United Kingdom

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• William R. Bamlet,

  Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

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• Marie-Christine Boutron-Ruault,

  Affiliation Inserm, (Institut National de la Santé et de la Recherche Médicale) and Institut Gustave Roussy, Villejuif, France

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• Julie E. Buring,

  Affiliations Divisions of Preventive Medicine and Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, Massachusetts, United States of America

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• Paige M. Bracci,

  Affiliation Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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• Federico Canzian,

  Affiliation Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Sandra Clipp,

  Affiliation George W. Comstock Center for Public Health Research and Prevention, Hagerstown, Maryland, United States of America

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• Michelle Cotterchio,

  Affiliation Cancer Care Ontario and Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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• Eric J. Duell,

  Affiliation Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain

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• Joanne Elena,

  Affiliation Division of Cancer Control and Population Science, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

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• J. Michael Gaziano,

  Affiliations Divisions of Preventive Medicine and Aging, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, United States of America

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• Edward L. Giovannucci,

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Michael Goggins,

  Affiliation Departments of Oncology, Pathology and Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Göran Hallmans,

  Affiliation Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden

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• Manal Hassan,

  Affiliation Department of Gastrointestinal Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America

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• Amy Hutchinson,

  Affiliation Core Genotyping Facility, SAIC-Frederick Inc., NCI-Frederick, Frederick, Maryland, United States of America

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• David J. Hunter,

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Charles Kooperberg,

  Affiliation Program in Biostatistics and Biomathematics, Division of Public Health, Fred Hutchinson Cancer Research Center, Seattle, Washington, Massachusetts, United States of America

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• Robert C. Kurtz,

  Affiliation Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Simin Liu,

  Affiliation Departments of Epidemiology, Medicine and Obstetrics & Gynecology Director, Center for Metabolic Disease Prevention, University of California Los Angeles, Los Angeles, California, United States of America

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• Kim Overvad,

  Affiliation Section of Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark

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• Domenico Palli,

  Affiliation Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO Florence, Italy

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• Alpa V. Patel,

  Affiliation Department of Epidemiology, American Cancer Society, Atlanta, Georgia, United States of America

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• Kari G. Rabe,

  Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

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• Xiao-Ou Shu,

  Affiliation Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, United States of America

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• Nadia Slimani,

  Affiliation International Agency for Research on Cancer, Lyon, France

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• Geoffrey S. Tobias,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Dimitrios Trichopoulos,

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece

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• Stephen K. Van Den Eeden,

  Affiliation Division of Research, Kaiser Permanente, Northern California Region, Oakland, California, United States of America

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• Paolo Vineis,

  Affiliation Imperial College London, London, United Kingdom

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• Jarmo Virtamo,

  Affiliation Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland

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• Jean Wactawski-Wende,

  Affiliation Department of Social and Preventive Medicine, University at Buffalo, State University of New York Buffalo, Buffalo, New York, United States of America

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• Brian M. Wolpin,

  Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Herbert Yu,

  Affiliation Department of Epidemiology and Public Health, Yale University School of Public Health, School of Medicine, New Haven, Connecticut, United States of America

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• Kai Yu,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Anne Zeleniuch-Jacquotte,

  Affiliations Department of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America, New York University Cancer Institute, New York, New York, United States of America

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• Stephen J. Chanock,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Robert N. Hoover,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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• Patricia Hartge,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, Maryland, United States of America

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•  [ ... ],
• Peter Kraft

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

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