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Genomic Deregulation of the E2F/Rb Pathway Leads to Activation of the Oncogene EZH2 in Small Cell Lung Cancer

  • Bradley P. Coe ,

    Contributed equally to this work with: Bradley P. Coe, Kelsie L. Thu

    Affiliation Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada

  • Kelsie L. Thu ,

    Contributed equally to this work with: Bradley P. Coe, Kelsie L. Thu

    kthu@bccrc.ca

    Affiliation Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada

  • Sarit Aviel-Ronen,

    Affiliation Pathology Department, Sheba Medical Centre, Tel-Hashomer, Israel

  • Emily A. Vucic,

    Affiliation Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada

  • Adi F. Gazdar,

    Affiliation Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

  • Stephen Lam,

    Affiliation Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada

  • Ming-Sound Tsao,

    Affiliations Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada, Department of Pathology, Princess Margaret Hospital University Health Network, Toronto, Canada

  • Wan L. Lam

    Affiliation Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada

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