Glycosylation on Hemagglutinin Affects the Virulence and Pathogenicity of Pandemic H1N1/2009 Influenza A Virus in Mice

Yan Zhang; Jiping Zhu; Yongtao Li; Konrad C. Bradley; Jiyue Cao; Huanchun Chen; Meilin Jin; Hongbo Zhou

doi:10.1371/journal.pone.0061397

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Open Access

Peer-reviewed

Research Article

Glycosylation on Hemagglutinin Affects the Virulence and Pathogenicity of Pandemic H1N1/2009 Influenza A Virus in Mice

Yan Zhang ,

Contributed equally to this work with: Yan Zhang, Jiping Zhu

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Jiping Zhu ,

Contributed equally to this work with: Yan Zhang, Jiping Zhu

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Yongtao Li,

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Konrad C. Bradley,

Affiliation Department of Microbiology and Immunology, Emory University School of Medicine, O. Wayne Rollins Research Center, Atlanta, Georgia, United States of America
⨯
Jiyue Cao,

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Huanchun Chen,

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Meilin Jin,

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯
Hongbo Zhou

* E-mail: hbzhou@mail.hzau.edu.cn

Affiliation State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China
⨯

Glycosylation on Hemagglutinin Affects the Virulence and Pathogenicity of Pandemic H1N1/2009 Influenza A Virus in Mice

Yan Zhang,
Jiping Zhu,
Yongtao Li,
Konrad C. Bradley,
Jiyue Cao,
Huanchun Chen,
Meilin Jin,
Hongbo Zhou

x

Published: April 24, 2013
https://doi.org/10.1371/journal.pone.0061397

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H1N1
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