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Open Access

Peer-reviewed

Research Article

A Yeast Purification System for Human Translation Initiation Factors eIF2 and eIF2Bε and Their Use in the Diagnosis of CACH/VWM Disease

  • Rogerio A. de Almeida,

    Affiliation Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

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  • Anne Fogli,

    Affiliations Laboratoire GReD (Génétique, Reproduction et Développement), Faculté de Médecine, INSERM U1103 CNRS 6293, Clermont-Ferrand, France, Université de Clermont, UFR Médecine, Clermont-Ferrand, France, Centre Hospitalier Universitaire de Clermont-Ferrand, Service de Biochimie Médicale et Biologie Moléculaire, Clermont-Ferrand, France

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  • Marina Gaillard,

    Affiliation Laboratoire GReD (Génétique, Reproduction et Développement), Faculté de Médecine, INSERM U1103 CNRS 6293, Clermont-Ferrand, France

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  • Gert C. Scheper,

    Current address: Crucell Holland BV, Leiden, The Netherlands

    Affiliation Department of Pediatrics, VU University Medical Centre, Amsterdam, The Netherlands

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  • Odile Boesflug-Tanguy,

    Affiliations INSERM U676, Hopital Robert Debré, Paris, France, Université Paris Diderot, Sorbonne Cité, UMR U676, Paris, France, APHP, Hopital Robert Debré, Pediatric Neurology and Metabolic Diseases, Reference Center for Leukodystrophies, Paris, France

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  • Graham D. Pavitt

    graham.pavitt@manchester.ac.uk

    Affiliation Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

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