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DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the ω-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways

  • John Paul SanGiovanni ,

    jpsangio@post.harvard.edu

    Affiliation Clinical Trials Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  • Jing Chen,

    Affiliation Department of Ophthalmology, Harvard Medical School, The Children’s Hospital, Boston, Massachusetts, United States of America

  • Przemyslaw Sapieha,

    Affiliation Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec, Canada

  • Christopher M. Aderman,

    Affiliation Department of Ophthalmology, Harvard Medical School, The Children’s Hospital, Boston, Massachusetts, United States of America

  • Andreas Stahl,

    Affiliation Department of Ophthalmology, University Eye Hospital Freiburg, Freiburg, Germany

  • Traci E. Clemons,

    Affiliation The EMMES Corp., Rockville, Maryland, United States of America

  • Emily Y. Chew,

    Affiliation Clinical Trials Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  • Lois E. H. Smith

    Affiliation Department of Ophthalmology, Harvard Medical School, The Children’s Hospital, Boston, Massachusetts, United States of America

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