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Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study

  • Didier Jutras-Aswad,

    Current address: Department of Psychiatry, Université de Montréal, Montreal, Quebec, Canada; CRCHUM, Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada

    Affiliation Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America

  • Michelle M. Jacobs,

    Affiliations Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

  • Georgia Yiannoulos,

    Affiliation Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America

  • Panos Roussos,

    Affiliation Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America

  • Panos Bitsios,

    Affiliation Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece

  • Yoko Nomura,

    Affiliations Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Psychology, Queens College, Queens, New York, United States of America

  • Xun Liu,

    Affiliations Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America, Institute of Psychology, Chinese Academy of Sciences, Beijing, People’s Republic of China

  • Yasmin L. Hurd

    Yasmin.hurd@mssm.edu

    Affiliations Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece, Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, James J Peters VA Medical Center, New York, New York, United States of America

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