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Combined Blockade of ADP Receptors and PI3-Kinase p110β Fully Prevents Platelet and Leukocyte Activation during Hypothermic Extracorporeal Circulation

  • Stefanie Krajewski ,

    krajewski@thg-lab.de

    Affiliation Department of Anesthesiology and Intensive Care Medicine, University of Tübingen, Tübingen, Germany

  • Julia Kurz,

    Affiliation Department of Anesthesiology and Intensive Care Medicine, University of Tübingen, Tübingen, Germany

  • Tobias Geisler,

    Affiliation Department of Cardiology, University of Tübingen, Tübingen, Germany

  • Karlheinz Peter,

    Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

  • Hans Peter Wendel,

    Affiliation Department of Thoracic, Cardiac and Vascular Surgery, University of Tübingen, Tübingen, Germany

  • Andreas Straub

    Affiliation Department of Anesthesiology and Intensive Care Medicine, University of Tübingen, Tübingen, Germany

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