A Non-VH1-69 Heterosubtypic Neutralizing Human Monoclonal Antibody Protects Mice against H1N1 and H5N1 Viruses

Donata De Marco; Nicola Clementi; Nicasio Mancini; Laura Solforosi; Guisella J. Moreno; Xiangjie Sun; Terrence M. Tumpey; Larisa V. Gubareva; Vasiliy Mishin; Massimo Clementi; Roberto Burioni

doi:10.1371/journal.pone.0034415

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Peer-reviewed

Research Article

A Non-VH1-69 Heterosubtypic Neutralizing Human Monoclonal Antibody Protects Mice against H1N1 and H5N1 Viruses

Donata De Marco ,

Contributed equally to this work with: Donata De Marco, Nicola Clementi, Nicasio Mancini

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Nicola Clementi ,

Contributed equally to this work with: Donata De Marco, Nicola Clementi, Nicasio Mancini

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Nicasio Mancini ,

Contributed equally to this work with: Donata De Marco, Nicola Clementi, Nicasio Mancini

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Laura Solforosi,

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Guisella J. Moreno,

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Xiangjie Sun,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Terrence M. Tumpey,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Larisa V. Gubareva,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Vasiliy Mishin,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Massimo Clementi,

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯
Roberto Burioni

* E-mail: burioni.roberto@hsr.it

Affiliation Laboratory of Microbiology and Virology, Vita-Salute San Raffaele University, Milan, Italy
⨯

A Non-VH1-69 Heterosubtypic Neutralizing Human Monoclonal Antibody Protects Mice against H1N1 and H5N1 Viruses

Donata De Marco,
Nicola Clementi,
Nicasio Mancini,
Laura Solforosi,
Guisella J. Moreno,
Xiangjie Sun,
Terrence M. Tumpey,
Larisa V. Gubareva,
Vasiliy Mishin,
Massimo Clementi

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Published: April 4, 2012
https://doi.org/10.1371/journal.pone.0034415

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H1N1
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