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Activation of Wnt Signaling by Chemically Induced Dimerization of LRP5 Disrupts Cellular Homeostasis

  • Payam Shahi ,

    Contributed equally to this work with: Payam Shahi, Dongsu Park

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Dongsu Park ,

    Contributed equally to this work with: Payam Shahi, Dongsu Park

    Current address: Massachusetts General Hospital Center for Regenerative Medicine, Harvard Stem Cell Institute, Boston, Massachusetts, United States of America

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Adam C. Pond,

    Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

  • Mamatha Seethammagari,

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Shin-Heng Chiou,

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Kyucheol Cho,

    Affiliation Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

  • Julienne L. Carstens,

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • William K. Decker,

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Pierre D. McCrea,

    Affiliation Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

  • Michael M. Ittmann,

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

  • Jeffrey M. Rosen,

    Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

  • David M. Spencer

    dspencer@bcm.edu

    Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

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