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Open Access

Peer-reviewed

Research Article

Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling

  • Li Sun ,

    Contributed equally to this work with: Li Sun, Yaling Xing

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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  • Yaling Xing ,

    Contributed equally to this work with: Li Sun, Yaling Xing

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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  • Xiaojuan Chen,

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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  • Yang Zheng,

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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  • Yudong Yang,

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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  • Daniel B. Nichols,

    Affiliation Department of Microbiology and Immunology, Loyola University of Chicago Stritch School of Medicine, Maywood, Illinois, United States of America

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  • Mark A. Clementz,

    Affiliation Department of Microbiology and Immunology, Loyola University of Chicago Stritch School of Medicine, Maywood, Illinois, United States of America

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  • Bridget S. Banach,

    Affiliation Department of Microbiology and Immunology, Loyola University of Chicago Stritch School of Medicine, Maywood, Illinois, United States of America

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  • Kui Li,

    Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

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  • Susan C. Baker ,

    sbaker1@lumc.edu (SCB); chenzb@bmi.ac.cn (ZC)

    Affiliation Department of Microbiology and Immunology, Loyola University of Chicago Stritch School of Medicine, Maywood, Illinois, United States of America

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  • Zhongbin Chen

    sbaker1@lumc.edu (SCB); chenzb@bmi.ac.cn (ZC)

    Affiliation Division of Infection and Immunity, Department of Electromagnetic and Laser Biology, Beijing Institute of Radiation Medicine, Beijing, China

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