Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints

• Christopher R. E. McEvoy ,

  * E-mail: cmcevoy@unimelb.edu.au

  Current address: Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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• Ruben Cloete,

  Current address: South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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• Borna Müller,

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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• Anita C. Schürch,

  Affiliation Tuberculosis Reference Laboratory, National Institute for Public Health and the Environment, Centre for Infectious Disease Control, (CIb/LIS, pb 22), Bilthoven, The Netherlands

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• Paul D. van Helden,

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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• Sebastien Gagneux,

  Affiliations Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland, Division of Mycobacterial Research, Medical Research Council, National Institute for Medical Research, London, United Kingdom

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• Robin M. Warren,

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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• Nicolaas C. Gey van Pittius

  Affiliation Department of Science and Technology, National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa

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