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Open Access

Peer-reviewed

Research Article

An Osteoblast-Derived Proteinase Controls Tumor Cell Survival via TGF-beta Activation in the Bone Microenvironment

  • Sophie Thiolloy,

    Affiliation Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee, United States of America

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  • James R. Edwards,

    Affiliation Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

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  • Barbara Fingleton,

    Affiliation Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee, United States of America

    ⨯
  • Daniel B. Rifkin,

    Affiliation Department of Cell Biology, New York University School of Medicine, New York, New York, United States of America

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  • Lynn M. Matrisian,

    Affiliation Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee, United States of America

    ⨯
  • Conor C. Lynch

    conor.lynch@moffitt.org

    Affiliation Tumor Biology Department, H. Lee Moffitt Cancer Center, Tampa, Florida, United States of America

    ⨯

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