A Unique Role of GATA1s in Down Syndrome Acute Megakaryocytic Leukemia Biology and Therapy

• Ana C. Xavier ,

  Contributed equally to this work with: Ana C. Xavier, Holly Edwards

  Affiliation Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan, United States of America

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• Holly Edwards ,

  Contributed equally to this work with: Ana C. Xavier, Holly Edwards

  Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America

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• Alan A. Dombkowski,

  Affiliations Division of Pharmacology and Toxicology, Children's Hospital of Michigan, Detroit, Michigan, United States of America, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, United States of America

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• Tugce B. Balci,

  Affiliation IWK Health Centre, Department of Pediatrics, Dalhousie University, Halifax, Canada

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• Jason N. Berman,

  Affiliation IWK Health Centre, Department of Pediatrics, Dalhousie University, Halifax, Canada

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• Graham Dellaire,

  Affiliation Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, Canada

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• Chengzhi Xie,

  Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America

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• Steven A. Buck,

  Affiliation Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan, United States of America

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• Larry H. Matherly,

  Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan, United States of America

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• Yubin Ge,

  Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America

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• Jeffrey W. Taub

  * E-mail: jtaub@med.wayne.edu

  Affiliations Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan, United States of America, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America, IWK Health Centre, Department of Pediatrics, Dalhousie University, Halifax, Canada

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