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Open Access

Peer-reviewed

Research Article

The Role of Endosomal Escape and Mitogen-Activated Protein Kinases in Adenoviral Activation of the Innate Immune Response

  • Jeffrey S. Smith,

    Affiliation Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, Maryland, United States of America

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  • Zhili Xu,

    Affiliation Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, Maryland, United States of America

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  • Jie Tian,

    Affiliation Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, Maryland, United States of America

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  • Donna J. Palmer,

    Affiliation Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Philip Ng,

    Affiliation Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Andrew P. Byrnes

    andrew.byrnes@fda.hhs.gov

    Affiliation Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, Maryland, United States of America

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