Sample Size Requirements for Studies of Treatment Effects on Beta-Cell Function in Newly Diagnosed Type 1 Diabetes

• John M. Lachin ,

  * E-mail: jml@bsc.gwu.edu

  Affiliation The Biostatistics Center, The George Washington University, Rockville, Maryland, United States of America

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• Paula L. McGee,

  Affiliation The Biostatistics Center, The George Washington University, Rockville, Maryland, United States of America

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• Carla J. Greenbaum,

  Affiliation Benaroya Research Institute, Seattle, Washington, United States of America

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• Jerry Palmer,

  Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America

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• Mark D. Pescovitz †,

  † Deceased.

  Affiliation Department of Surgery and Microbiology/Immunology, Indiana University Medical Center, Indianapolis, Indiana, United States of America

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• Peter Gottlieb,

  Affiliation Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, Colorado, United States of America

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• Jay Skyler,

  Affiliation Diabetes Research Institute, University of Miami School of Medicine, Miami, Florida, United States of America

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• Type 1 Diabetes Trial Network

  ¶Members of the Type 1 Diabetes Trial Network are shown in the Supporting Information (Supplement S1).

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