H3N2 Influenza Infection Elicits More Cross-Reactive and Less Clonally Expanded Anti-Hemagglutinin Antibodies Than Influenza Vaccination

• M. Anthony Moody ,

  Contributed equally to this work with: M. Anthony Moody, Ruijun Zhang

  * E-mail: moody007@mc.duke.edu

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States of America

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• Ruijun Zhang ,

  Contributed equally to this work with: M. Anthony Moody, Ruijun Zhang

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Emmanuel B. Walter,

  Affiliation Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States of America

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• Christopher W. Woods,

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America, Institute for Genome Sciences & Policy, Duke University Medical Center, Durham, North Carolina, United States of America, Division of Infectious Diseases, Durham Veteran's Affairs Medical Center, Durham, North Carolina, United States of America

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• Geoffrey S. Ginsburg,

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America, Institute for Genome Sciences & Policy, Duke University Medical Center, Durham, North Carolina, United States of America

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• Micah T. McClain,

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Division of Infectious Diseases, Durham Veteran's Affairs Medical Center, Durham, North Carolina, United States of America

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• Thomas N. Denny,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Xi Chen,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Supriya Munshaw,

  Affiliation Department of Biostatistics & Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America

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• Dawn J. Marshall,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• John F. Whitesides,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Mark S. Drinker,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Joshua D. Amos,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Thaddeus C. Gurley,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Joshua A. Eudailey,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Andrew Foulger,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Katherine R. DeRosa,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Robert Parks,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• R. Ryan Meyerhoff,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Jae-Sung Yu,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• Daniel M. Kozink,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Brice E. Barefoot,

  Affiliation Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

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• Elizabeth A. Ramsburg,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Surender Khurana,

  Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America

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• Hana Golding,

  Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America

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• Nathan A. Vandergrift,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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• S. Munir Alam,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Georgia D. Tomaras,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Thomas B. Kepler,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biostatistics & Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America

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• Garnett Kelsoe,

  Affiliation Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Hua-Xin Liao,

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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•  [ ... ],
• Barton F. Haynes

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

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