Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease

• Naoki Yahata,

  Affiliations Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Masashi Asai,

  Affiliations Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Saitama, Japan

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• Shiho Kitaoka,

  Affiliations Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Kazutoshi Takahashi,

  Affiliation Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

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• Isao Asaka,

  Affiliations Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan

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• Hiroyuki Hioki,

  Affiliations Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Takeshi Kaneko,

  Affiliation Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Kei Maruyama,

  Affiliation Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan

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• Takaomi C. Saido,

  Affiliation Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Saitama, Japan

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• Tatsutoshi Nakahata,

  Affiliation Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

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• Takashi Asada,

  Affiliation Department of Neuropsychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan

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• Shinya Yamanaka,

  Affiliations Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Yamanaka iPS Cell Special Project, Japan Science and Technology Agency, Saitama, Japan

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• Nobuhisa Iwata ,

  * E-mail: haruhisa@cira.kyoto-u.ac.jp (HI); iwata-n@nagasaki-u.ac.jp (NI)

  Affiliations Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Saitama, Japan, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

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• Haruhisa Inoue

  * E-mail: haruhisa@cira.kyoto-u.ac.jp (HI); iwata-n@nagasaki-u.ac.jp (NI)

  Affiliations Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan, Yamanaka iPS Cell Special Project, Japan Science and Technology Agency, Saitama, Japan

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