Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis

Kang-Jie Chen; Sheng-Zhang Lin; Lin Zhou; Hai-Yang Xie; Wu-Hua Zhou; Ahmed Taki-Eldin; Shu-Sen Zheng

doi:10.1371/journal.pone.0024671

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Peer-reviewed

Research Article

Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis

Kang-Jie Chen,

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Sheng-Zhang Lin,

Affiliations Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Department of General Surgery, Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, China
⨯
Lin Zhou,

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Hai-Yang Xie,

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Wu-Hua Zhou,

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Ahmed Taki-Eldin,

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Shu-Sen Zheng

* E-mail: zysxswzsz@zju.edu.cn

Affiliation Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯

Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis

Kang-Jie Chen,
Sheng-Zhang Lin,
Lin Zhou,
Hai-Yang Xie,
Wu-Hua Zhou,
Ahmed Taki-Eldin,
Shu-Sen Zheng

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Published: September 14, 2011
https://doi.org/10.1371/journal.pone.0024671

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Regulatory T cells
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Hepatocellular carcinoma
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T cells
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Cancers and neoplasms
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Breast cancer
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Differentiated tumors
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Chemokines
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Prognosis
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