Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure

• Ying-Ying Wang,

  Affiliation Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Samuel K. Lai,

  Current address: Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  Affiliation Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Conan So,

  Affiliation Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Craig Schneider,

  Affiliation Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Richard Cone,

  Affiliation Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Justin Hanes

  * E-mail: hanes@jhu.edu

  Affiliations Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Environmental Health Sciences, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America, Center for Cancer Nanotechnology Excellence, Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, United States of America, Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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