Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang; Catalin Barbacioru; Ellen Nordman; Siqin Bao; Caroline Lee; Xiaohui Wang; Brian B. Tuch; Edith Heard; Kaiqin Lao; M. Azim Surani

doi:10.1371/journal.pone.0021208

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Open Access

Peer-reviewed

Research Article

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang ,

Contributed equally to this work with: Fuchou Tang, Catalin Barbacioru

Affiliations Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom, Biodynamic Optical Imaging Center, School of Life Sciences, Peking University, Beijing, China
⨯
Catalin Barbacioru ,

Contributed equally to this work with: Fuchou Tang, Catalin Barbacioru

Affiliation Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America
⨯
Ellen Nordman,

Affiliation Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America
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Siqin Bao,

Affiliation Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom
⨯
Caroline Lee,

Affiliation Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom
⨯
Xiaohui Wang,

Affiliation Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America
⨯
Brian B. Tuch,

Affiliation Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America
⨯
Edith Heard,

Affiliation CNRS UMR3215, INSERM U934, Institut Curie, Paris, France
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Kaiqin Lao ,

* E-mail: a.surani@gurdon.cam.ac.uk (MAS); kaiqinlao@gmail.com (KL)

Affiliation Genetic Systems, Applied Biosystems, Life Technologies, Foster City, California, United States of America
⨯
M. Azim Surani

* E-mail: a.surani@gurdon.cam.ac.uk (MAS); kaiqinlao@gmail.com (KL)

Affiliation Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom
⨯

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang,
Catalin Barbacioru,
Ellen Nordman,
Siqin Bao,
Caroline Lee,
Xiaohui Wang,
Brian B. Tuch,
Edith Heard,
Kaiqin Lao,
M. Azim Surani

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Published: June 23, 2011
https://doi.org/10.1371/journal.pone.0021208

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Blastomeres
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Alleles
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Gene expression
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Heterozygosity
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Homozygosity
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Transcriptome analysis
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Oocytes
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Genetic loci
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