Influenza A Virus Nucleoprotein Exploits Hsp40 to Inhibit PKR Activation

Kulbhushan Sharma; Shashank Tripathi; Priya Ranjan; Purnima Kumar; Rebecca Garten; Varough Deyde; Jacqueline M. Katz; Nancy J. Cox; Renu B. Lal; Suryaprakash Sambhara; Sunil K. Lal

doi:10.1371/journal.pone.0020215

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Open Access

Peer-reviewed

Research Article

Influenza A Virus Nucleoprotein Exploits Hsp40 to Inhibit PKR Activation

Kulbhushan Sharma ,

Contributed equally to this work with: Kulbhushan Sharma, Shashank Tripathi

Affiliation Virology Group, International Centre for Genetic Engineering & Biotechnology, New Delhi, India
⨯
Shashank Tripathi ,

Contributed equally to this work with: Kulbhushan Sharma, Shashank Tripathi

Affiliation Virology Group, International Centre for Genetic Engineering & Biotechnology, New Delhi, India
⨯
Priya Ranjan,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Purnima Kumar,

Affiliation Virology Group, International Centre for Genetic Engineering & Biotechnology, New Delhi, India
⨯
Rebecca Garten,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Varough Deyde,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Jacqueline M. Katz,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Nancy J. Cox,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Renu B. Lal,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Suryaprakash Sambhara,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Sunil K. Lal

* E-mail: sunillal@icgeb.res.in

Affiliation Virology Group, International Centre for Genetic Engineering & Biotechnology, New Delhi, India
⨯

Influenza A Virus Nucleoprotein Exploits Hsp40 to Inhibit PKR Activation

Kulbhushan Sharma,
Shashank Tripathi,
Priya Ranjan,
Purnima Kumar,
Rebecca Garten,
Varough Deyde,
Jacqueline M. Katz,
Nancy J. Cox,
Renu B. Lal,
Suryaprakash Sambhara

x

Published: June 15, 2011
https://doi.org/10.1371/journal.pone.0020215

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Influenza A virus
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Phosphorylation
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Influenza viruses
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Transfection
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Small interfering RNA
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Influenza
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H5N1
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