Altered Gene Expression in Pulmonary Tissue of Tryptophan Hydroxylase-1 Knockout Mice: Implications for Pulmonary Arterial Hypertension

Richard B. Rothman; Jean L. Cadet; Christina M. Dersch; Michael T. McCoy; Elin Lehrmann; Kevin G. Becker; Michael Bader; Natalia Alenina; Michael H. Baumann

doi:10.1371/journal.pone.0017735

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Peer-reviewed

Research Article

Altered Gene Expression in Pulmonary Tissue of Tryptophan Hydroxylase-1 Knockout Mice: Implications for Pulmonary Arterial Hypertension

Richard B. Rothman ,

* E-mail: rrothman@mail.nih.gov

Affiliation Translational Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America
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Jean L. Cadet,

Affiliation Molecular Neuropsychiatry Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America
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Christina M. Dersch,

Affiliation Translational Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America
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Michael T. McCoy,

Affiliation Molecular Neuropsychiatry Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America
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Elin Lehrmann,

Affiliation Gene Expression and Genomics Unit, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
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Kevin G. Becker,

Affiliation Gene Expression and Genomics Unit, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
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Michael Bader,

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany
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Natalia Alenina,

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany
⨯
Michael H. Baumann

Affiliation Translational Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, United States of America
⨯

Altered Gene Expression in Pulmonary Tissue of Tryptophan Hydroxylase-1 Knockout Mice: Implications for Pulmonary Arterial Hypertension

Richard B. Rothman,
Jean L. Cadet,
Christina M. Dersch,
Michael T. McCoy,
Elin Lehrmann,
Kevin G. Becker,
Michael Bader,
Natalia Alenina,
Michael H. Baumann

x

Published: March 25, 2011
https://doi.org/10.1371/journal.pone.0017735

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Genetically modified animals
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Gene expression
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Tryptophan
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