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Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease

  • Xianting Li,

    Affiliation Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America

  • Qing Jun Wang,

    Current address: Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

    Affiliation Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York, United States of America

  • Nina Pan,

    Affiliation Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America

  • Sangkyu Lee,

    Affiliation Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois, United States of America

  • Yingming Zhao,

    Affiliation Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois, United States of America

  • Brian T. Chait,

    Affiliation Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York, United States of America

  • Zhenyu Yue

    zhenyu.yue@mssm.edu

    Affiliation Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America

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