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Open Access

Peer-reviewed

Research Article

Self-Renewal of Acute Lymphocytic Leukemia Cells Is Limited by the Hedgehog Pathway Inhibitors Cyclopamine and IPI-926

  • Tara L. Lin ,

    tlin@lsuhsc.edu (TLL); matsuwi@jhmi.edu (WM)

    Affiliation Section of Hematology and Oncology, Department of Internal Medicine, LSU Health Sciences Center, New Orleans, Louisiana, United States of America

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  • Qiuju H. Wang,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Patrick Brown,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Craig Peacock,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Akil A. Merchant,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Sarah Brennan,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Evan Jones,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Karen McGovern,

    Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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  • D. Neil Watkins,

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Kathleen M. Sakamoto,

    Affiliation Gwynne Hazen Cherry Memorial Laboratories, Department of Pediatrics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

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  • William Matsui

    tlin@lsuhsc.edu (TLL); matsuwi@jhmi.edu (WM)

    Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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