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Linking Genotype and Phenotype of Saccharomyces cerevisiae Strains Reveals Metabolic Engineering Targets and Leads to Triterpene Hyper-Producers

  • Karina M. Madsen ,

    Contributed equally to this work with: Karina M. Madsen, Gupta D. B. R. K. Udatha, Saori Semba

    Affiliation Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark

  • Gupta D. B. R. K. Udatha ,

    Contributed equally to this work with: Karina M. Madsen, Gupta D. B. R. K. Udatha, Saori Semba

    Affiliation Department of Chemical and Biological Engineering, Industrial Biotechnology, Chalmers University of Technology, Gothenburg, Sweden

  • Saori Semba ,

    Contributed equally to this work with: Karina M. Madsen, Gupta D. B. R. K. Udatha, Saori Semba

    Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan

  • Jose M. Otero,

    Affiliations Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark, Department of Chemical and Biological Engineering, Systems Biology, Chalmers University of Technology, Gothenburg, Sweden

  • Peter Koetter,

    Affiliation Institute for Microbiology, Johann Wolfgang Goethe-University of Frankfurt, Frankfurt, Germany

  • Jens Nielsen,

    Affiliation Department of Chemical and Biological Engineering, Systems Biology, Chalmers University of Technology, Gothenburg, Sweden

  • Yutaka Ebizuka,

    Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan

  • Tetsuo Kushiro,

    Affiliation Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan

  • Gianni Panagiotou

    gpa@bio.dtu.dk

    Affiliations Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan, Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark

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