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Full Factorial Analysis of Mammalian and Avian Influenza Polymerase Subunits Suggests a Role of an Efficient Polymerase for Virus Adaptation

  • Olive T. W. Li,

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

  • Michael C. W. Chan,

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

  • Cynthia S. W. Leung,

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

  • Renee W. Y. Chan,

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

  • Yi Guan,

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

  • John M. Nicholls,

    Affiliation Department of Pathology, The University of Hong Kong, Hong Kong SAR, China

  • Leo L. M. Poon

    llmpoon@hkucc.hku.hk

    Affiliation State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China

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