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Bioavailability of Orally Administered rhGM-CSF: A Single-Dose, Randomized, Open-Label, Two-Period Crossover Trial

  • Wenping Zhang ,

    Contributed equally to this work with: Wenping Zhang, Zhengbing Lv

    Affiliations Institute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, China, The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Zhengbing Lv ,

    Contributed equally to this work with: Wenping Zhang, Zhengbing Lv

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Zuoming Nie,

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Guogang Chen,

    Affiliation Zhejiang Chinagene Biopharmaceutical Co., Ltd., Haining, China

  • Jian Chen,

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Qing Sheng,

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Wei Yu,

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

  • Yongfeng Jin,

    Affiliation Institute of Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, China

  • Xiangfu Wu,

    Affiliations The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China, Institute of Biochemistry, the Chinese Academy of Sciences, Shanghai, China

  • Yaozhou Zhang

    yaozhou@chinagene.com

    Affiliation The Key Laboratory of Bioreactor and Biopharmacy of Zhejiang Province, Institute of Biochemistry, Zhejiang Sci-Tech University, Hangzhou, China

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