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Open Access

Peer-reviewed

Research Article

Targeted Disruption of the PME-1 Gene Causes Loss of Demethylated PP2A and Perinatal Lethality in Mice

  • Silvia Ortega-Gutiérrez,

    Affiliations The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, La Jolla, California, United States of America

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  • Donmienne Leung,

    Affiliations The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, La Jolla, California, United States of America

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  • Scott Ficarro,

    Affiliation The Genomics Institute for the Novartis Foundation, San Diego, California, United States of America

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  • Eric C. Peters,

    Affiliation The Genomics Institute for the Novartis Foundation, San Diego, California, United States of America

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  • Benjamin F. Cravatt

    cravatt@scripps.edu

    Affiliations The Skaggs Institute for Chemical Biology and Department of Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, La Jolla, California, United States of America

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