Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity

• Ji-Yeon Lee ,

  Contributed equally to this work with: Ji-Yeon Lee, Heike Muenzberg, Oksana Gavrilova

  Affiliation Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Heike Muenzberg ,

  Contributed equally to this work with: Ji-Yeon Lee, Heike Muenzberg, Oksana Gavrilova

  Affiliation Department of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Oksana Gavrilova ,

  Contributed equally to this work with: Ji-Yeon Lee, Heike Muenzberg, Oksana Gavrilova

  Affiliation Mouse Metabolic Core Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Jacquelyn A. Reed,

  Affiliation University of Cincinnati, Cincinnati, Ohio, United States of America

  ⨯
• Darlene Berryman,

  Affiliation Ohio University, Athens, Ohio, United States of America

  ⨯
• Eneida C. Villanueva,

  Affiliation Department of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Gwendolyn W. Louis,

  Affiliation Department of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Gina M. Leinninger,

  Affiliation Department of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Stefano Bertuzzi,

  Affiliation Mammalian Development Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Randy J. Seeley,

  Affiliation University of Cincinnati, Cincinnati, Ohio, United States of America

  ⨯
• Gertraud W. Robinson,

  Affiliation Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Martin G. Myers Jr.,

  Affiliation Department of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Lothar Hennighausen

  *E-mail: hennighausen@nih.gov

  Affiliation Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯