Site-Directed Mutations in the C-Terminal Extension of Human αB-Crystallin Affect Chaperone Function and Block Amyloid Fibril Formation

• Teresa M. Treweek,

  Affiliations Department of Chemistry, University of Wollongong, Wollongong, New South Wales, Australia, Graduate School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia

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• Heath Ecroyd,

  Affiliation School of Chemistry and Physics, The University of Adelaide, Adelaide, South Australia, Australia

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• Danielle M. Williams,

  Affiliation School of Chemistry and Physics, The University of Adelaide, Adelaide, South Australia, Australia

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• Sarah Meehan,

  Affiliation The University Chemical Laboratory, University of Cambridge, Cambridge, United Kingdom

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• John A. Carver,

  Affiliation School of Chemistry and Physics, The University of Adelaide, Adelaide, South Australia, Australia

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• Mark J. Walker

  *To whom correspondence should be addressed. E-mail: mwalker@uow.edu.au

  Affiliation School of Biological Sciences, University of Wollongong, Wollongong, New South Wales, Australia

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