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Development of New Mouse Lung Tumor Models Expressing EGFR T790M Mutants Associated with Clinical Resistance to Kinase Inhibitors

  • Lucia Regales,

    Affiliation Pao Lab, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Marissa N. Balak,

    Affiliation Pao Lab, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Yixuan Gong,

    Affiliation Pao Lab, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Katerina Politi,

    Affiliation Varmus Lab, Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Ayana Sawai,

    Affiliation Rosen Lab, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Carl Le,

    Affiliation Imaging and Spectroscopic Physics Service, Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Jason A. Koutcher,

    Affiliation Imaging and Spectroscopic Physics Service, Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • David B. Solit,

    Affiliation Solit Lab, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Neal Rosen,

    Affiliation Rosen Lab, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • Maureen F. Zakowski,

    Affiliation Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • William Pao

    To whom correspondence should be addressed. E-mail: paow@mskcc.org

    Affiliations Pao Lab, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, 7 Department of Medicine, Weill Medical College of Cornell University, New York, New York, United States of America

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