Experimental Rugged Fitness Landscape in Protein Sequence Space

• Yuuki Hayashi,

  Affiliation Department of Bioinformatic Engineering, Osaka University, Suita, Osaka, Japan

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• Takuyo Aita,

  Affiliations Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/JST, Saitama Small Enterprise Promotion Corporation SKIP City, Kawaguchi, Saitama, Japan, Department of Functional Materials Science, Saitama University, Saitama, Japan

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• Hitoshi Toyota,

  Affiliation Department of Biotechnology, Osaka University, Suita, Osaka, Japan

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• Yuzuru Husimi,

  Affiliation Department of Functional Materials Science, Saitama University, Saitama, Japan

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• Itaru Urabe,

  Affiliation Department of Biotechnology, Osaka University, Suita, Osaka, Japan

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• Tetsuya Yomo

  *To whom correspondence should be addressed. E-mail: yomo@ist.osaka-u.ac.jp

  Affiliations Department of Bioinformatic Engineering, Osaka University, Suita, Osaka, Japan, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan, Expoloratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency (JST), Suita, Osaka, Japan

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